DRUG PARTICLES OBTAINED BY FREEZING ONTO A COLD SURFACE
摘要
The present invention is a method for preparing micron-sized or submicron-sized drug particles comprising contacting a solution comprising a poorly water soluble drug substance and at least one freezable organic solvent with a cold surface so as to freeze the solution; and removing the organic solvent. The resulting particles are also disclosed, as are several embodiments of an apparatus that can be used in performing the method of the present invention.
申请公布号
WO2004064808(A1)
申请公布日期
2004.08.05
申请号
WO2003US25338
申请日期
2003.08.12
申请人
DOW GLOBAL TECHNOLOGIES INC.;SCHERZER, BRIAN, D.;EVANS, JONATHAN, C.;HITT, JAMES, E.
发明人
SCHERZER, BRIAN, D.;EVANS, JONATHAN, C.;HITT, JAMES, E.