发明名称 SUBSTITUTED 4-AMINO-1-(PYRIDYLMETHYL) PIPERIDINE AS MUSCARINIC RECEPTOR ANTAGONISTS
摘要 This invention provides 4-amino-1-(pyridylmethyl) piperidine of formula (I) and related compounds and pharmaceutically acceptable salts thereof which are useful as muscarinic receptor antagonists. This invention also provides pharmaceutical compositions containing such compounds; processes and intermediates useful for preparing such compounds; and methods for treating disease conditions mediated by muscarinic receptors, such as overactive bladder, irritable bowel syndrome and chronic obstructive pulmonary disease, using such compounds.
申请公布号 WO2004041806(A3) 申请公布日期 2004.08.05
申请号 WO2003US34444 申请日期 2003.10.29
申请人 THERAVANCE, INC.;MAMMEN, MATHAI;WILSON, RICHARD;CHEN, YAN;DUNHAM, SARAH;HUGHES, ADAM;HUSFELD, CRAIG;JI, YU-HUA;LI, LI;MISCHKI, TREVOR;STERGIADES, IOANNA 发明人 MAMMEN, MATHAI;WILSON, RICHARD;CHEN, YAN;DUNHAM, SARAH;HUGHES, ADAM;HUSFELD, CRAIG;JI, YU-HUA;LI, LI;MISCHKI, TREVOR;STERGIADES, IOANNA
分类号 A61P13/10;C07D401/00;C07D401/14 主分类号 A61P13/10
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