摘要 |
PROBLEM TO BE SOLVED: To obtain a prophylactic or therapeutic agent for autoimmune diseases and an immunosuppressant. SOLUTION: The prophylactic or therapeutic agent for autoimmune diseases and the immunosuppressant comprise as an effective ingredient a compound represented by formula (I) [wherein W is a 9-17C saturated or unsaturated carbon chain optionally bearing a hydroxy group; X is a 11-25C saturated or unsaturated carbon chain optionally bearing a hydroxy group; Y is (CH<SB>2</SB>)<SB>a</SB>-CH=CH-(CH<SB>2</SB>)<SB>b</SB>, (CH<SB>2</SB>)<SB>a</SB>(wherein (a) and (b) are each an integer of 0-5; and (a+b) is at most 5), S(O)<SB>0-2</SB>CH<SB>2</SB>or NHCH<SB>2</SB>; Z is CO or SO<SB>2</SB>; R is a CH<SB>2</SB>OH, CO<SB>2</SB>H, CO<SB>2</SB>OCH<SB>2</SB>CO<SB>2</SB>H or CH<SB>2</SB>OSO<SB>3</SB>H group; and R<SB>0</SB>is an OH, NH<SB>2</SB>or NHAc group] or a pharmacologically acceptable salt thereof. COPYRIGHT: (C)2004,JPO&NCIPI
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