| 摘要 |
The invention relates to an otorhinological delivery device comprising at least one pharmaceutically active agent. According to the invention the devi ce comprises a core comprising said at least one pharmaceutically active agent wherein said core is made of an elastomer composition selected from the grou p consisting of poly(dimethylsiloxane), a siloxane-based elastomer comprising 3,3,3-trifluoropropyl groups attached to the Si~atoms of the siloxane units, a siloxane-based elastomer comprising poly(alkylene oxide) groups and mixtures thereof, and a membrane encasing said core, said membrane being made of a sa me or a different elastomer composition than said core, said elastomer composition being selected from the group consisting of poly(dimethylsiloxane), a siloxane-based elastomer comprising 3,3,3- trifluoropropyl groups attached to the Si~atoms of the siloxane units, a siloxane-based elastomer comprising poly(alkylene oxide) groups and mixtures thereof. The invention is characterized in that the pharmaceutically active agent is selected from the group comprising anti-allergic agents, anti- inflammatory agents, anti-fungicides, glucocorticoids and mixtures thereof.< /SDOAB>
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