发明名称 |
Therapeutic targets for treatment of HCV infections, methods of treating HCV infections and compounds useful therefor |
摘要 |
The present invention relates to the human cellular protein glutathione peroxidase-gastrointestinal as a target for medical intervention against Hepatitis C virus (HCV) infections. Furthermore, the present invention relates to a method for the detection of compounds useful for prophylaxis and/or treatment of Hepatitis C virus infections and a method for detecting Hepatitis C virus infections in an individual or in cells. Also compositions, compounds, nucleic acid molecules (such as aptamers), mono- or polyclonal antibodies are disclosed which are effective for the treatment of HCV infections, and methods for prophylaxis and/or treatment of Hepatitis C virus infections or for the regulation of Hepatitis C virus production are disclosed.
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申请公布号 |
US2004152073(A1) |
申请公布日期 |
2004.08.05 |
申请号 |
US20030723719 |
申请日期 |
2003.11.26 |
申请人 |
HERGET THOMAS;COTTEN MATTHEW;OBERT SABINE;KLEBL BERT |
发明人 |
HERGET THOMAS;COTTEN MATTHEW;OBERT SABINE;KLEBL BERT |
分类号 |
A61K31/00;A61K38/00;A61K38/21;A61K48/00;C12N9/08;C12Q1/28;G01N33/573;G01N33/576;(IPC1-7):C07H21/04;C12Q1/70;G01N33/53 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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