发明名称 |
REGULATOR/PROMOTER FOR TUNABLE GENE EXPRESSION AND METABOLITE SENSING |
摘要 |
A method for the facile and inexpensive inducible expression of heterologous genes has been discovered. The yhcS regulator gene has been found to be inducible by aromatic carboxylic acids and to alter the expression of operons in the LysR gene family, including the yhcRQP operon, common in enteric bacteria. Heterologous nucleic acid molecules placed under the control of yhcS responsive promoters may be overexpressed in response to the presence of inexpensive aromatic carboxylic acids. |
申请公布号 |
WO2004065555(A2) |
申请公布日期 |
2004.08.05 |
申请号 |
WO2004US01551 |
申请日期 |
2004.01.16 |
申请人 |
E.I. DU PONT DE NEMOURS AND COMPANY;VAN DYK, TINA, K. |
发明人 |
VAN DYK, TINA, K. |
分类号 |
C07K14/245;C12N15/70 |
主分类号 |
C07K14/245 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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