METHODS AND COMPOSITIONS FOR MODULATING ACTIVATOR PROTEIN 1
摘要
This invention provides novel AP-1 modulatory polypeptides. The invention also provides methods for screening modulators of AP-1 transcription factor activities. The methods comprise first screening test agents for modulators of an AP-1-modulatory polypeptide and then further screening the identified modulating agents for modulators of AP-1 transcription factor activities. The invention further provides methods and pharmaceutical compositions for modulating AP-1 transcription factor activities in a cell and for treating diseases and conditions mediated by abnormal cellular proliferation.
申请公布号
WO2004043370(A3)
申请公布日期
2004.08.05
申请号
WO2003US35367
申请日期
2003.11.05
申请人
IRM LLC;CHANDA, SUMIT;WHITE, SUHAILA;HOGENESCH, JOHN, B.;CALDWELL, JEREMY, S.
发明人
CHANDA, SUMIT;WHITE, SUHAILA;HOGENESCH, JOHN, B.;CALDWELL, JEREMY, S.