Substituted benzopyran derivatives against arrhythmia

摘要

This invention relates to benzopyran derivatives of the formula (1) or the formula (2) wherein R<1 >and R<2 >represent independently of each other hydrogen atom or C1-6alkyl group, R<3 >represents hydroxyl group or C1-6 alkylcarbonyloxy group, R<4 >represents hydrogen atom or C1-6 alkyl group, R<5 >represents C1-6 alkyl group substituted with C6-14 aryl group or heteroaryl group, R<6 >represents C1-6 alkyl group, C1-6 alkoxy group, halogen atom, nitro group, C(O)NH2, C(O)NHR<8 >or C(O)NR<8>R<9>, or pharmaceutically acceptable salts thereof. These compounds are useful as an antiarrhythmic agent.