| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To obtain a composition and to provide method for ameliorating various effects of UV (ultraviolet) A and UVB radiations from the sun. <P>SOLUTION: The composition contains an ingredient that prevents photoaging from MED (Minimum Erythema Dose) or <MED radiation, such as a retinoid, certains other compounds (such as N-acetylcysteine, 2-furyldioxime, and vitamin C) and optionally other MMP (matrix metalloproteinase) inhibitors such as tetracyclines, and/or compounds that inhibit the P-450-mediated metabolism of retinoids such as ketoconazole, and other azole compounds. The method comprises coating the composition before exposure to sunlight according to the component of the composition. The coating has to be applied 7-48 hours before the exposure. <P>COPYRIGHT: (C)2004,JPO&NCIPI</p> |
