发明名称 |
DEVICES AND METHODS FOR FOCUSING ANALYTES IN AN ELECTRIC FIELD GRADIENT II |
摘要 |
Devices are provided for separating and focusing analytes, comprising a separation chamber and electrodes separated from the separation chamber by a membrane. The electrodes are operative to generate an electric field in the separation chamber. Molecular sieve in the separation chamber is operative to shift the location at which a stationary focused band of the analyte forms under a given set of focusing process parameters. Methods are provided for separating and focusing charged analytes, comprising introducing a first fluid comprising at least one charged analyte into the separation chamber of a device as just described, applying an electric field gradient to the separation chamber to focus the charged analyte at a location in the separation chamber. Methods are provided for separating and focusing un-charged (including inadequately charged) analytes, comprising introducing a fluid comprising at least the uncharged analyte and lipids, micelles and/or vesicles into the separation chamber of a device as just described, and applying an electric field gradient to the separation chamber to focus the analyte (in association with the lipids, micelles and/or vesicles) at a location in the separation chamber. |
申请公布号 |
WO2004065619(A2) |
申请公布日期 |
2004.08.05 |
申请号 |
WO2004US00659 |
申请日期 |
2004.01.12 |
申请人 |
PROTASIS CORPORATION;STRAND, DAVID;LEATZOW, DAN, M. |
发明人 |
STRAND, DAVID;LEATZOW, DAN, M. |
分类号 |
C12Q;G01N27/26;G01N27/447 |
主分类号 |
C12Q |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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