Antimicrobial lenses displaying extended efficacy, processes to prepare them and methods of their use

摘要

This invention relates to antimicrobial ophthalmic devices containing silver releasing compounds and methods for their production. The antimicrobial lenses of the present invention have percent haze of less than about 200% and have a release rate constant, calculated using a first order kinetics equation of up to about 1 days<-1 >and an initial silver concentration of at least about 10 ppm.