| 摘要 |
<p>The invention concerns a novel surface-functionalized carrier material with a polymeric surface and at least one linker compound according to the general formula (I), which is covalently bound to the surface. In the formula, P indicates the polymeric surface; R<SUP>2 </SUP>has the meaning OR<SUP>4 </SUP>or NR<SUP>4</SUP>R<SUP>5 </SUP>and R<SUP>1</SUP>, R<SUP>4 </SUP>and R<SUP>5</SUP>, independently of one another, indicate H, an alkyl group or an aryl group; R<SUP>3 </SUP>indicates H, an alkyl, an aryl, an acyl, an alkoxycarbonyl or an aryloxycarbonyl group; and the alkyl, aryl, acyl, alkoxycarbonyl and/or aryloxycarbonyl group of the radicals R<SUP>1</SUP>, R<SUP>3</SUP>, R<SUP>4 </SUP>and R<SUP>5</SUP>, independently of one another, are substituted or unsubstituted. The material according to the invention can be very easily produced by photochemical coupling and serves for the solid-phase synthesis of amino acids, peptides, proteins or molecules with at least one peptidic structural unit.</p> |
