发明名称 |
Diagnostic imaging technique |
摘要 |
The invention provides a method of generating an image of an animate human or non-human animal subject previously administered with a contrast agent involving generating an image of at least a part of said subject to which said contrast agent has distributed, characterised in that said contrast agent is a composition of matter of formula I V - L - R where V is a vector moiety having affinity for an angiogenesis-related endothelial cell receptor, L is a linker moiety or a bond and R is a detectable moiety, characterised in that V is a non-peptidic organic group, or V is peptidic and R is a macromolecular or particulate species providing a multiplicity of labels detectable in in vivo imaging.
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申请公布号 |
EP1442751(A1) |
申请公布日期 |
2004.08.04 |
申请号 |
EP20040007226 |
申请日期 |
1998.04.24 |
申请人 |
GE HEALTHCARE AS |
发明人 |
KLAVENESS, JO;TOLLESHAUG, HELGE;NAEVESTAD, ANNE;BLACK, CHRISTOPHER D.;WOLFE, HENRY R. |
分类号 |
C12N15/09;A61K47/48;A61K49/00;A61K49/08;A61K49/18;A61K49/22;A61K51/04;A61K51/08;A61K51/12;C07D233/02;C07D239/94;C07D401/12;(IPC1-7):A61K49/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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