Stable crystal of thiazolidinedione derivative and process for producing the same

摘要

A homogeneous crystal having excellent stability which is suitable for the industrial-scale production of 5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]benzamide (KRP-297). The novel crystal of KRP-297 is produced through recrystallization from an alcohol solvent. It is characterized by having diffraction angles (2theta) at at least 9.7°, 15.0°, and 22.5° in X-ray powder diffractometry.