发明名称 |
Trypsin substrate and diagnostic device, and method of using same |
摘要 |
A compound of the formula (I)wherein R<1 >is a protecting group for Nalpha, R<2 >is a protecting group for NG, and R<3 >is aryl, and wherein the compound of formula (I) is a trypsin substrate such that trypsin cleaves the O-C single bond, which liberates R<3>-OH; a diagnostic device comprising same; a method for preparing the diagnostic device; and a method of using the diagnostic device to detect levels of urinary trypsin inhibitor in a biological sample; and a diagnostic kit for detecting levels of urinary trypsin inhibitor in a biological sample.
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申请公布号 |
US6770764(B2) |
申请公布日期 |
2004.08.03 |
申请号 |
US20010844816 |
申请日期 |
2001.04.30 |
申请人 |
BAYER CORPORATION |
发明人 |
COREY PAUL F.;FELMAN STEVEN W.;REHM GARY E.;PUGIA MICHAEL J. |
分类号 |
G01N33/493;C07C279/36;C07D207/36;C07D209/36;C07D277/20;C07D277/34;C07D311/16;C12M1/34;C12Q1/37;G01N33/53;(IPC1-7):C07D207/36;C07D309/30;C07D311/00;C07D275/02;C07D209/04;C07D295/04;C07C311/00;C07C229/00 |
主分类号 |
G01N33/493 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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