发明名称 |
Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith |
摘要 |
Pharmaceutical compositions that include a drug-oligomer conjugate, a fatty acid component, and a bile salt component are described. The drug is covalently coupled to an oligomeric moiety. The fatty acid component and the bile salt component are present in a weight-to-weight ratio of between 1:5 and 5:1. Methods of treating diseases in a subject in need of such treatment using such pharmaceutical compositions are also provided, as are methods of providing such pharmaceutical compositions.
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申请公布号 |
US6770625(B2) |
申请公布日期 |
2004.08.03 |
申请号 |
US20020235284 |
申请日期 |
2002.09.05 |
申请人 |
NOBEX CORPORATION |
发明人 |
SOLTERO RICHARD;EKWURIBE NNOCHIRI N.;OPAWALE FOYEKE;REHLAENDER BRUCE;HICKEY ANTHONY;BOVET LI LI |
分类号 |
A61K47/48;(IPC1-7):A61K38/02;A61K38/23;A61K38/28;A61K47/12 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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