Process for producing L-lysine by fermentation

摘要

A process for producing L-lysine which comprises culturing in an appropriate medium a bacterium belonging to the genus Serratia, which has been transformed by introducing a DNA encoding a dihydrodipicolinic acid synthetase originating in a bacterium belonging to the genus Escherichia or Serratia having a mutation of releasing the feedback inhibition by L-lysine and another DNA encoding an aspartokinase originating in a bacterium belonging to the genus Escherichia or Serratia having a mutation of releasing the feedback inhibition by L-lysine into the cells, and harvesting the L-lysine thus accumulated in the culture.