PREPARATION FOR INHIBITING PROLIFERATION OF LUNG CANCER CELL WITH RNAi SEQUENCE WITH RESPECT TO MGC5627 GENE, METHOD OF MANUFACTURING THE SAME AND METHOD OF INHIBITING PROLIFERATION OF LUNG CANCER CELL THEREBY

摘要

PURPOSE: Provided is a preparation for inhibiting the proliferation of lung cancer cells which expresses RNAi with respect to MGC5627 genes, and effectively inhibits the growth of the lung cancer tissues, and the colony formation and the anchorage independency thereof. CONSTITUTION: The lung cancer cell proliferation inhibitor comprises the RNAi sequence identified by SEQ ID NO 2 for inhibiting the gene expression of MGC5627 identified by SEQ ID NO 1 to treat lung cancers. The RNAi sequence is expressed by the human U6 promoter cassette. The RNAi expression vector with the concentration of 2 micro grams/1x100000 is introduced into the lung cancer cell together with cationic liposome of 1-20 micro grams/1x100000 several times for 4-15 days.