| 发明名称 |
PHARMACEUTICAL COMPOSITIONS OF 5, 7, 14-TRIAZATETRACYCLO [10.3.1.0(2,11).0(4,9)] -HEXADECA -2(11) 3, 5, 7, 9-PENTAENE. |
| 摘要 |
<p>The present invention is directed to controlled-release (CR) oral pharmaceutical dosage forms of 5, 8, 14-triazatetracyclo [10.3.1.02,11.04,9] -hexadeca-2(11 ), 3, 5, 7, 9-pentaene, 1, and pharmaceutically acceptable salts thereof, and methods of using them to reduce nicotine addiction or aiding in the cessation or lessening of tobacco use while reducing nausea as an adverse effect. The present invention also relates to an immediate-release (IR) low dosage composition having a stable formulation with uniform drug distribution and potency.</p> |
