发明名称 |
OPTIMIZING siRNA BY RNAi ANTISENSE |
摘要 |
<p>The present invention regards a novel method for identifying potent siRNA sequences that may be used to modify the expression of a target gene sequence. Specifically, the present invention provides a method for the identification of optimal siRNA targeting sites by utilising RNAi antisense. Further, the present invention provides siRNA molecules identified through the present screening method and pharmaceutical preparations comprising said siRNA molecules.</p> |
申请公布号 |
WO2004063375(A1) |
申请公布日期 |
2004.07.29 |
申请号 |
WO2004NO00007 |
申请日期 |
2004.01.14 |
申请人 |
PRYDZ, HANS;AMARZGUIOUI, MOHAMMED;HOLEN, TORGEIR |
发明人 |
PRYDZ, HANS;AMARZGUIOUI, MOHAMMED;HOLEN, TORGEIR |
分类号 |
C12N15/11;(IPC1-7):C12N15/11;C12Q1/68;A61K31/713 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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