发明名称 |
MOLECULAR CARDIOTOXICOLOGY MODELING |
摘要 |
The present invention is based on the elucidation of the global changes in gene expression and the identification of toxicity markers in tissues or cel ls exposed to a known cardiotoxin. The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of gen es characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes.
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申请公布号 |
CA2512774(A1) |
申请公布日期 |
2004.07.29 |
申请号 |
CA20042512774 |
申请日期 |
2004.01.08 |
申请人 |
GENE LOGIC, INC. |
发明人 |
PORTER, MARK W.;MENDRICK, DONNA L.;HIGGS, BRANDON;JOHNSON, KORY R.;ELASHOFF, MICHAEL;CASTLE, ARTHUR |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;G06F19/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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