Cancer therapy using multiple antibodies from different species directed against the tumor3

摘要

This invention describes a method whereby antitumor antibodies obtained from different species and directed against a variety of antigens present in tumors can be used for immunotherapy of cancer. Some of these antibodies may have a direct inhibitory effect upon the tumor, or they may labeled with radionuclides or cytotoxic agents and used as "carriers" to transport the cytotoxic agent to the tumor where they will have maximum effect. By employing a succession of antitumor antibodies produced from different species the risk of the cancer patient developing an allergic reaction to the foreign antibodies is minimized.