| 发明名称 |
PERSISTENT EXPRESSION OF CANDIDATE MOLECULE IN PROLIFERATINGSTEM AND PROGENITOR CELLS FOR DELIVERY OF THERAPEUTIC PRODUCTS |
| 摘要 |
<p num="1"><br/><br/><br/>A method of obtaining and the resulting isolated progenitor or stem cell <br/>population of proliferating cells persistently expressing a candidate <br/>molecule. Further, novel products of ex vivo gene product (e.g., protein) <br/>production and treating symptoms of neurological or neurodegenerative <br/>disorders are also provided. Fig. 15 illustrates vector used in the presently <br/>claimed invention, wherein IRES-neo sequences were cloned into the 3~ non-<br/>coding sequence (flanking exon 28) of the mouse Polr2a locus.<br/>
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| 申请公布号 |
CA2513226(A1) |
申请公布日期 |
2004.07.29 |
| 申请号 |
CA20042513226 |
申请日期 |
2004.01.13 |
| 申请人 |
RAO, MAHENDRA, S.;CAPECCHI, MARIO R. |
发明人 |
RAO, MAHENDRA S.;CAPECCHI, MARIO R. |
| 分类号 |
A61K35/12;A61K48/00;C12N5/0797;C12N15/90;(IPC1-7):A61K48/00;C12N5/00;C12N5/08;C12N15/63;C12N15/87;C12N15/00 |
主分类号 |
A61K35/12 |
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