| 发明名称 |
HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS |
| 摘要 |
A compound having the following formula (I): wherein R1 is N-containing heterocyclic ring optionally substituted with one or more suitable substituent(s), R2 is hydroxyamino, R3 is hydrogen or a suitable substituent , L1 is -(CH2#191)n#191- (wherein n is an integer of 0 to 6) optionally substituted with one or more suitable substituent(s), wherein one or more methylene(s) may be replaced with suitable heteroatom(s), and L2 is lower alkenylene, or a salt thereof. The compound is useful as a histone deacetyla se inhibitor.
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| 申请公布号 |
CA2513436(A1) |
申请公布日期 |
2004.07.29 |
| 申请号 |
CA20042513436 |
申请日期 |
2004.01.13 |
| 申请人 |
ASTELLAS PHARMA INC. |
发明人 |
ISHIBASHI, NAOKI;SATOH, SHIGEKI;URANO, YASUHARU;KAMIJO, KAZUNORI |
| 分类号 |
A61P35/00;C07C57/58;C07C61/40;C07C211/50;C07C211/52;C07C233/22;C07C233/31;C07C233/43;C07C233/44;C07C233/51;C07C271/28;C07D213/75;C07D233/54;C07D233/64;C07D233/68;C07D233/70;C07D233/90;C07D235/12;C07D235/16;C07D239/46;C07D317/66;C07D401/04;C07D405/12;C07D405/14;C07D409/04;C07D471/04;C07D473/08;C07D491/04;(IPC1-7):C07D235/16;C07D403/04;C07D487/04;A61K31/416;A61K31/417;A61K31/418 |
主分类号 |
A61P35/00 |
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