发明名称 |
COMBINATION THERAPY FOR ANTICOAGULATION |
摘要 |
A combination anticoagulation medicament including vitamin K with warfarin in an oral form is described. Between 50 and 5000 milligrams of vitamin K are combined in a single oral medication with 0.5 to 15 milligrams of warfarin for administration. The combination of vitamin K with warfarin in a single orally dosed form is a novel approach to improving the effectiveness of anticoagulation. The combination allows for broader application of warfarin in medical anticoagulation and reduces the variability of anticoagulation due to the influences of diet, additional medications, nutritional status, changes in physical condition, and potentially other factors. Use of the combination therapy improves the safety of warfarin as an appropriate anticoagulant for many medical conditions. |
申请公布号 |
WO2004062582(A2) |
申请公布日期 |
2004.07.29 |
申请号 |
WO2004US00191 |
申请日期 |
2004.01.07 |
申请人 |
FLACCO-NESSELROAD FAMILY TRUST;NESSELROAD, III, JAMES, M. |
发明人 |
NESSELROAD, III, JAMES, M. |
分类号 |
A61K;A61K6/00;A61K31/12;A61K31/122;A61K31/35;A61K31/366;A61K31/37;A61P7/02 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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