| 发明名称 |
METHODS AND COMPOSITIONS FOR INDUCING TUMOR-SPECIFIC CYTOTOXICITY. |
| 摘要 |
<p>The invention relates to tumor-specific viral replication and/or expression using conditionally replicative viral vectors in which the expression of a gene product essential for viral replication is controlled by an H19 regulatory sequence. The invention provides such viral vectors, methods of making such vectors and methods of administering such vectors. The compositions and methods of the invention are useful in the treatment of cancer and hyperproliferative disorders.</p> |
| 申请公布号 |
MXPA04003732(A) |
申请公布日期 |
2004.07.23 |
| 申请号 |
MX2004PA03732 |
申请日期 |
2002.10.22 |
| 申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWUNIVERSITY OF JERUSALEM |
发明人 |
SUHAIL AYESH |
| 分类号 |
C12N15/09;A61K35/76;A61K48/00;A61P35/00;A61P43/00;C07K14/65;C12N15/86;C12N15/861;(IPC1-7):A61K48/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
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