发明名称 COMPOSITION CAPABLE OF ACTIVATING NATURAL KILLER CELLS AND PROCESS FOR PRODUCING THE SAME, COMPOSITION CONTAINING NATURAL KILLER CELLS ACTIVATED BY THE FORMER COMPOSITION AND PROCESS FOR PRODUCING THE SAME
摘要 <p>A composition capable of activating natural killer cells comprising a fraction which is substantially free from uronic acid, contains polysaccharides comprising xylose, arabinose and glucose and is insoluble in an organic acid solvent. This fraction is obtained by subjecting barley shochu (distilled spirit) stillage to solid-liquid separation to give a liquid, subjecting this liquid to an ion exchange treatment using an ion exchange resin to give a fraction (a) not adsorbed by the ion exchange resin, or subjecting the above-described liquid to an adsorption separation treatment using a synthetic adsorbent to give a fraction (b) not adsorbed by the synthetic adsorbent, then subjecting this fraction (b) to an ion exchange treatment using an ion exchange resin to give the above-described fraction (a), concentrating the thus obtained fraction (a) by ultrafiltration using an ultrafiltration membrane to give a liquid concentrate, and adding the above-described organic solvent to the liquid concentrate. A composition containing natural killer cells having been inactivated with the use of the above composition.</p>
申请公布号 WO2004061090(A1) 申请公布日期 2004.07.22
申请号 WO2004JP00003 申请日期 2004.01.05
申请人 SANWA SHURUI CO., LTD.;BARLEY FERMENTATION TECHNOLOGIES, INC.;NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE;OMORI, TOSHIRO;UMEMOTO, YASUFUMI;FURUTA, YOSHIFUMI;HOKAZONO, HIDEKI;FURUTERA, MIHOKO;OHBA, HIDEKI_____________________________________- 发明人 OMORI, TOSHIRO;UMEMOTO, YASUFUMI;FURUTA, YOSHIFUMI;HOKAZONO, HIDEKI;FURUTERA, MIHOKO;OHBA, HIDEKI
分类号 A61K31/716;A61K35/14;A61K36/00;A61K36/06;A61K36/899;A61P1/16;A61P31/12;A61P35/00;A61P35/02;A61P37/02;A61P43/00;C12N5/0783;C12P1/00;(IPC1-7):C12N5/06;A61K35/78;A61K35/72;A61K35/74;C12N5/08 主分类号 A61K31/716
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