发明名称 |
Prodrugs of vancomycin with hydrolysis resistant polymer linkages |
摘要 |
Vancomycin-polymer conjugates are disclosed. In preferred aspects, polymer residues which are hydrolysis resistant in vitro, are selectively attached to the sugar amino and/or N-methyl amino groups of vancomycin and related compounds. Vancomycin-polymer conjugates made by the methods and methods of treatment using the conjugates are also disclosed.
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申请公布号 |
US2004142858(A1) |
申请公布日期 |
2004.07.22 |
申请号 |
US20030705740 |
申请日期 |
2003.11.11 |
申请人 |
GREENWALD RICHARD B.;ZHAO HONG |
发明人 |
GREENWALD RICHARD B.;ZHAO HONG |
分类号 |
A61K38/14;C07K9/00;C08H1/00;C12Q;(IPC1-7):A61K38/14 |
主分类号 |
A61K38/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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