发明名称 |
Triazoloquinazoline and pyrazolotriazolopyrimidine derivatives, medicinal compositions, adenosine a3 receptor affinity agents, ocular tension lowering agents, preparations for preventing and treating glaucoma and method of lowering ocular tension |
摘要 |
The present invention provides triazoloquinazoline and pyrazolotriazolopyrimidine derivatives represented by the following general formula (1): wherein R<1 >and R<2 >represent the same groups as those described in the description; and A represents a pyrazole or benzene ring which is optionally substituted with the groups described in the description. These derivatives exhibit an affinity to an adenosine A3 receptor and also have an intraocular-pressure reducing effect, and are useful for prevention or treatment of glaucoma.
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申请公布号 |
US2004142952(A1) |
申请公布日期 |
2004.07.22 |
申请号 |
US20040470974 |
申请日期 |
2004.02.18 |
申请人 |
OKAMURA TAKASHI;KUROGI YASUHISA;NISHIKAWA HIROSHI |
发明人 |
OKAMURA TAKASHI;KUROGI YASUHISA;NISHIKAWA HIROSHI |
分类号 |
A61P9/10;A61P9/12;A61P11/06;A61P11/10;A61P11/14;A61P17/04;A61P27/06;A61P29/00;A61P35/02;A61P37/08;A61P43/00;C07D487/14;(IPC1-7):C07D487/14;A61K31/519 |
主分类号 |
A61P9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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