发明名称 Hydrazinopeptoids and their uses for treating cancers
摘要 Compounds of general formula (I), wherein: n represents an integer from 1 to 10; R1 and R6, independently of each other, represent a hydrogen atom, a group useful for protecting nitrogen atoms in peptide synthesis or a group of formula COR or -CH2COR, wherein R represents a hydrogen atom, an alkyl group of 1 to 10 carbon atoms, a -COORa group wherein Ra represents H or an alkyl group, a primary -NH2 amino group or a secondary or tertiary amine, an alkoxy group, a phenyl group or a pyridinium group; R2, R3, R4 and R5, independently of one another, represent a hydrogen atom, an alkyl group of 1 to 10 carbon atoms; Y represents CH2 and Z represents CO, or Y represents CO and Z represents CH2, for preparing a medicine for treating tumoral pathologies or neurodegenerative diseases such as Alzheimer's or Lehn's disease.
申请公布号 US2004142851(A1) 申请公布日期 2004.07.22
申请号 US20040432986 申请日期 2004.04.07
申请人 BONNEMAINS YANNICK;BOUGET KARINE;FLOC'H MICHELE;LE GREL PHILIPPE;AUBIN SANDRINE 发明人 BONNEMAINS YANNICK;BOUGET KARINE;FLOC'H MICHELE;LE GREL PHILIPPE;AUBIN SANDRINE
分类号 A61K31/198;A61K31/21;A61K31/4425;A61P25/00;A61P25/28;A61P35/00;A61P43/00;C07C243/34;C07C281/02;C07C281/06;C07D213/20;C07F5/02;(IPC1-7):A61K31/275;A61K38/00;A61K31/22;A61K31/16 主分类号 A61K31/198
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