TREATMENT OF DRY EYE BY RESTORING 15-LIPOXYGENASE ACTIVITY TO OCULAR SURFACE CELLS
摘要
The present invention provides compositions comprising the 15-lipoxygenase-1 (15-LO-1) or 15-lipoxyngenase-2 (15-LO-2) gene such that 15-LO-1 or 15-LO-2 protein expression is replaced or replenished in the ocular surface epithelium of postmenopausal women suffering from dry eye. Thus, methods for treatment of dry eye in postmenopausal women are further provided.
申请公布号
WO2004060274(A2)
申请公布日期
2004.07.22
申请号
WO2003US33139
申请日期
2003.10.17
申请人
ALCON, INC.;YANNI, JOHN, M.;GAMACHE, DANIEL, A.;MILLER, STEVEN, T.
发明人
YANNI, JOHN, M.;GAMACHE, DANIEL, A.;MILLER, STEVEN, T.
