Method for stabilising particle size distribution of powder active principle dispersed in a liquid and uses thereof

摘要

The invention concerns a method for stabilising particle size distribution of a powdery active principle, when the latter is dispersed in a liquid. Said method is characterised in that it consists in dispersing said active principle in a glycol ether or a mixture of glycol ethers. The invention also concerns the uses of said method and, in particular for pharmaceutical compositions and galenic forms comprising a retinoid as active principle, and suited for providing the latter with improved bioavailability (suprabioavailability) after oral administration.