发明名称 Nucleic acid-based modulation of gene expression in the vascular endothelial growth factor pathway
摘要 The present invention relates to nucleic acid molecules, including dsRNA, siRNA, antisense, 2,5-A chimeras, aptamers, and enzymatic nucleic acid molecules, such as hammerhead ribozymes, DNAzymes, and allozymes, which modulate the expression of vascular endothelial growth factor receptor (VEGF) and/or vascular endothelial growth factor receptor (VEGFr) genes for the treatment and/or diagnosis of female reproductive disorders and conditions, including but not limited to endometriosis, endometrial carcinoma, gynecologic bleeding disorders, irregular menstrual cycles, ovulation, premenstrual syndrome (PMS), and menopausal dysfunction.
申请公布号 US2004142895(A1) 申请公布日期 2004.07.22
申请号 US20030726236 申请日期 2003.12.02
申请人 SIRNA THERAPEUTICS, INC. 发明人 LOCKRIDGE JENNIFER;PAVCO PAMELA
分类号 A61K38/00;C12N15/113;(IPC1-7):A61K48/00 主分类号 A61K38/00
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