发明名称 |
METHOD OF DEUTERIZATION |
摘要 |
<p>A method of deuterizing a compound represented by the general formula [1]: R<1>-X-R<2> [1] (wherein R<1> represents alkyl, etc.; R<2> represents alkyl, hydroxy, etc.; and X represents carbonyl or hydroxymethylene), which comprises reacting the compound represented by the general formula [1] with a deuterium source in the presence of a catalyst selected among activated palladium, platinum, rhodium, ruthenium, nickel, and cobalt catalysts. By the method, deuterization, which has been conducted under severe conditions, can be conducted under neutral conditions. Even when the compound contains an unsaturated bond, it can be deuterized without reducing the unsaturated bond.</p> |
申请公布号 |
WO2004060831(A1) |
申请公布日期 |
2004.07.22 |
申请号 |
WO2003JP14182 |
申请日期 |
2003.11.07 |
申请人 |
WAKO PURE CHEMICAL INDUSTRIES, LTD.;ITO, NOBUHIRO;MAESAWA, TSUNEAKI;MUTO, KAZUSHIGE;HIROTA, KOSAKU;SAJIKI, HIRONAO |
发明人 |
ITO, NOBUHIRO;MAESAWA, TSUNEAKI;MUTO, KAZUSHIGE;HIROTA, KOSAKU;SAJIKI, HIRONAO |
分类号 |
C07B59/00;C07C29/00;C07C45/00;(IPC1-7):C07B59/00;C07C57/04;C07C31/02;C07C35/08;C07C35/29;C07C35/37;C07C49/04;C07C53/124;C07C53/10;C07C51/00;C07C49/453;C07C49/433;C07C49/08 |
主分类号 |
C07B59/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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