SOLID DISPERSIONS COMPRISING A HYGROSCOPIC AND/OR DELIQUESCENT DRUG

摘要

A pharmaceutical composition is provided, comprising a solid dispersion having a carrier medium that comprises (a) a matrix forming agent selected from hydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxypropylmethylcellulose phthalate, polyvinyl pyrrolidone, polyethylene glycol, polyglycolized glycerides, cyclodextrins and carbomers, and (b) a filler, and having a hygroscopic and/or deliquescent drug dispersed or dissolved in the carrier medium. The composition is acceptably non-hygroscopic.