发明名称 |
Methods for treating or preventing infections from coagulase-negative staphylococci |
摘要 |
Methods for treating or preventing infections from coagulase-negative staphylococci using proteins and polypeptides from coagulase-negative staphylococcal bacteria such as S. epidermidis, including proteins designated SdrF, SdrG and SdrH, and their effective fragments such as their respective A domains, are provided. Methods are also provided wherein antibodies that recognize the SdrG protein or its ligand binding A region are used to treat or prevent staphylococcal infection, and these methods can also be utilized to prevent the formation of infections on indwelling medical devices.
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申请公布号 |
US2004141997(A1) |
申请公布日期 |
2004.07.22 |
申请号 |
US20030690184 |
申请日期 |
2003.10.21 |
申请人 |
FOSTER TIMOTHY J.;MCCREA KIRK;HOOK MAGNUS A.O.;DAVIS STACEY;NI EIDHIN DEIRDRE;HARTFORD ORLA |
发明人 |
FOSTER TIMOTHY J.;MCCREA KIRK;HOOK MAGNUS A.O.;DAVIS STACEY;NI EIDHIN DEIRDRE;HARTFORD ORLA |
分类号 |
G01N33/50;A61K38/00;A61K39/00;A61K39/085;A61K39/395;A61K48/00;A61L27/00;A61L29/00;A61L31/00;A61P9/00;A61P17/02;A61P19/00;A61P31/04;C07K14/31;C07K16/12;C12N15/09;C12Q1/02;C12R1/44;C12R1/45;G01N33/15;G01N33/569;(IPC1-7):A61K48/00;A61K39/02 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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