发明名称 |
METHOD AND APPARATUS FOR DETERMINING GENE EXPRESSION LEVELS |
摘要 |
Techniques for analyzing gene expression levels are provided. In one aspect of the invention, the technique provides a method for determining a concentration level of a target nucleic acid, the target nucleic acid comprising at least one target oligonucleotide. The method determines: (i) a measure of affinity value of the target oligonucleotide with a probe oligonucleotide; and (ii) a hybridization intensity value for the target oligonucleotide and the probe oligonucleotide at a probe spot. The measure of affinity value and the hybridization intensity value are used to determine the concentration level of the target nucleic acid. |
申请公布号 |
WO2004061076(A2) |
申请公布日期 |
2004.07.22 |
申请号 |
WO2003US38698 |
申请日期 |
2003.12.05 |
申请人 |
INTERNATIONAL BUSINESS MACHINES CORPORATION |
发明人 |
GRINSTEIN, GEOFFREY;HELD, GLENN, ALLEN;TU, YUHAI |
分类号 |
C12N;C12Q1/68;G01N31/00;G06F19/00 |
主分类号 |
C12N |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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