| 摘要 |
This invention provides stable HIV-1 pre-fusion envelope glycoprotein trimeric complexes. This invention also provides related polypeptides and compositions comprising pharmaceutically acceptable particles and the trimeric complexes operably affixed thereto. This invention further provides related nucleic acids, vectors, host cells, compositions, production methods, and prophylactic and therapeutic methods. |
| 申请人 |
PROGENICS PHARMACEUTICALS, INC.;CORNELL RESEARCH FOUNDATION, INC.;MOORE, JOHN, P.;BINLEY, JAMES, M.;LU, MIN;OLSON, WILLIAM, C.;SCHULKE, NORBERT;GARDNER, JASON;MADDON, PAUL, J.;SANDERS, ROGIER |
发明人 |
MOORE, JOHN, P.;BINLEY, JAMES, M.;LU, MIN;OLSON, WILLIAM, C.;SCHULKE, NORBERT;GARDNER, JASON;MADDON, PAUL, J.;SANDERS, ROGIER |
