发明名称 |
Herpes simplex virus expressing foreign genes and method for treating cancers therewith |
摘要 |
An anti-cancer pharmaceutical composition includes a herpes simplex virus (HSV) vector into which a nucleic acid sequence encoding an anti-cancer agent selected from interleukin-12, GM-CSF, and CD has been inserted. A method of treatment of a patient suffering from cancer includes administering to the patient the anti-tumor pharmaceutical composition including an HSV vector having a nucleic acid sequence encoding an anti-cancer agent selected from interleukin-12, GM-CSF, and CD inserted therein.
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申请公布号 |
US6764675(B1) |
申请公布日期 |
2004.07.20 |
申请号 |
US20020009972 |
申请日期 |
2002.02.14 |
申请人 |
THE UAB RESEARCH FOUNDATION |
发明人 |
WHITLEY RICHARD J.;MARKERT JAMES MACDOWELL;GILLESPIE GEORGE YANCEY;PARKER JACQUELINE NESS |
分类号 |
A61K35/76;A61K38/00;A61K38/19;A61K38/20;A61K38/50;A61K48/00;C12N9/78;C12N15/869;(IPC1-7):A01N63/00 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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