| 摘要 |
FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to substituted phenylalkenoylguanidines and their pharmaceutically acceptable salts and physiologically functional derivatives. Invention describes compounds of the formula (Ia): ^ ^ wherein T1 and T2 mean independently: ^ ^ or hydrogen atom, and T1 and T2 can't represent hydrogen atom simultaneously; L-z means: ^ ^ wherein L means -C=C-, -NH-CH2-CH2-O-; R(E) means hydrogen atom, (C1-C4)-alkyl; R(1), R(2) mean hydrogen, fluorine, chlorine atom, CN, -SO2-CH3, -(C1-C4)-alkyl, -O-(C1-C4)-alkyl and their physiologically acceptable salts, physiologically derivatives and method for their preparing. These compounds can be used, for example, as medicinal agents for prophylaxis and treatment of cholelithiasis disease. ^ EFFECT: valuable medicinal properties of compounds. ^ 4 cl, 7 ex |
