发明名称 Methods and compositions comprising glycoprotein glycoforms
摘要 This invention relates to novel glycoprotein glycoform preparations comprising the substantially homogeneous glycoprotein glycoforms and combinations thereof. More particularly the invention relates to glycoprotein preparations comprising a particular Fc glycoforms and methods for producing, detecting, enriching and purifying the glycoforms. The invention further relates to immunoglobulins and especially antibodies comprising a CH2 domain having particular N-linked glycans. Provided are compositions including pharmaceutical compositions methods of using the preparations as well as articles of manufacture comprising the preparations.
申请公布号 US2004136986(A1) 申请公布日期 2004.07.15
申请号 US20030744844 申请日期 2003.12.23
申请人 GENENTECH, INC. 发明人 RAJU T. SHANTHA
分类号 C07K16/00;C07K16/24;C07K16/28;C07K16/32;C07K16/42;(IPC1-7):A61K39/395 主分类号 C07K16/00
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