发明名称 |
INDIVIDUAL METHODS FOR MEASUREMENT OF SPECIFIC LYMPHOCYTE FUNCTION |
摘要 |
<p>The present invention disclosed a method for successively measuring in vitro the responses of individual to immunocytes from organ transplants or tumor, which comprises the steps of: 1) adding antigen from donor or MHC/HLA molecular library including donor's MHC/HLA type or antigen from recipient self or its same tumor type to the sample from desired subject, and incubating for sufficient time for immunocytes activation, 2) separating and/or typing the immunocytes and measuring the activation index; thereof so-called antigen from the donor of organ transplants is whole-cell or subcelluar components having MHC/HLA or MHC/HLA molecular, or so-called antigen from recipient self is whole-cell of tumor or celluar extractives including most celluar components; this method also including make so-called antigen from individual self or non-tumor antigen as contrast for stimulating antigen.</p> |
申请公布号 |
WO2004059319(A1) |
申请公布日期 |
2004.07.15 |
申请号 |
WO2003CN01120 |
申请日期 |
2003.12.25 |
申请人 |
CHEN, GE;PEL-FREEZ BIOTECHNOLOGY (BEIJING) LTD.;LIU, XIANGJUN |
发明人 |
CHEN, GE;LIU, XIANGJUN |
分类号 |
C12Q1/04;C12Q1/24;C12Q1/70;G01N33/50;G01N33/53;G01N33/566;G01N33/569;(IPC1-7):G01N33/53 |
主分类号 |
C12Q1/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|