发明名称 METHOD FOR IDENTIFICATION OF ENZYMES THAT ARE EXPRESSED IN CERTAIN TUMOR TISSUE
摘要 The present invention relates to a method for identification of enzymes that are preferentially expressed in certain tumor tissue as compared with rapidly growing normal cells or tissue, use of said enzymes for the compound design to generate an active anticancer substance selectively in tumor tissue, compounds designed based on said enzymes, their pharmaceutically acceptable salts as well as pharmaceutical composition thereof.
申请公布号 UA77718(C2) 申请公布日期 2004.07.15
申请号 UA20040604831 申请日期 2002.11.18
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人
分类号 A61K31/337;A61K31/401;A61K31/426;A61K31/472;A61K31/506;A61K31/517;A61K31/519;A61K31/53;A61K31/537;A61K31/704;A61K31/706;A61K38/00;A61K47/48;A61P35/00;A61P43/00;C07K5/06;C07K7/06;C12N15/09;C12Q1/02;C12Q1/26;C12Q1/32;C12Q1/37;C12Q1/48;C12Q1/68;G01N33/15;G01N33/50;G01N33/573;G01N33/574;G01N37/00 主分类号 A61K31/337
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