发明名称 |
Use of corticotroph-derived glycoprotein hormone to treat inflammation and potentiate glucocorticoid action |
摘要 |
The use of corticotroph-derived glycoprotein hormone (CGH) to potentiate glucocorticoid action and to reduce glucocorticoid-induced adrenocortical suppression is described. CGH can be co-administered with glucocorticoids to enable a lower dosage of glucocorticoids to be used and to prevent or reduce glucocorticoid-induced side-effects. The invention additionally provides methods for the use of CGH as a replacement for glucocorticoids, or for treatment of a broad range of inflammatory states. Further provided are methods for purification of recombinant CGH.
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申请公布号 |
US2004138113(A1) |
申请公布日期 |
2004.07.15 |
申请号 |
US20030459000 |
申请日期 |
2003.06.10 |
申请人 |
KELLY JAMES D.;WEBSTER PHILIPPA J.;DILLON STACEY R.;O'HOGAN SHANNON L.;WOLF ANITRA |
发明人 |
KELLY JAMES D.;WEBSTER PHILIPPA J.;DILLON STACEY R.;O'HOGAN SHANNON L.;WOLF ANITRA |
分类号 |
G01N30/46;A61K38/00;A61K38/35;A61P1/04;A61P1/16;A61P3/04;A61P5/44;A61P5/46;A61P7/00;A61P7/04;A61P7/06;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P13/12;A61P17/00;A61P17/04;A61P17/06;A61P19/00;A61P19/02;A61P19/10;A61P25/00;A61P25/04;A61P25/18;A61P25/30;A61P29/00;A61P31/04;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P37/08;A61P39/00;A61P41/00;A61P43/00;C07K1/16;C07K14/575;C07K14/59;C07K14/72;C07K19/00;C12N5/10;C12N15/09;G01N30/88;G01N33/76;(IPC1-7):A61K38/24 |
主分类号 |
G01N30/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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