发明名称 QUINOLONES - 5-HT ANTAGONISTS AND THEIR USE
摘要 Provided herein is a compound having the formula (I) (R2 is typically a tertiary nitrogen atom, being either alkyl-substituted or member of a heterocyclic ring; R7 is typically a monocyclic or bicyclic aromatic ring or a heterocyclic ring) wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety, eating disorders, dementia, panic disorder, and sleep disorders. The compounds may also be useful in the treatment of gastrointestinal disorders, cardiovascular regulation, motor disorders, endocrine disorders, vasospasm and sexual dysfunction. The compounds are 5HT1B and 5HT1D antagonists. I
申请公布号 UA77012(C2) 申请公布日期 2004.07.15
申请号 UA20040403038 申请日期 2002.11.01
申请人 ASTRAZENECA AB 发明人
分类号 A61K31/496;C07D215/42;A61K31/537;A61K31/5377;A61K31/541;A61K31/551;A61P1/00;A61P1/14;A61P3/04;A61P5/00;A61P9/00;A61P15/00;A61P15/10;A61P21/00;A61P21/02;A61P25/14;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P43/00;C07D207/14;C07D215/233;C07D215/48;C07D241/04;C07D243/08;C07D265/30;C07D311/24;C07D311/66;C07D401/04;C07D401/12;C07D401/14;C07D405/04;C07D405/12;C07D405/14;C07D413/06;C07D413/12;C07D413/14;C07D417/04;C07D417/12;C07D521/00 主分类号 A61K31/496
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