发明名称 |
HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING |
摘要 |
<p>Exploitation of suitably functionalized heterocyclic molecules, in the design and synthesis of Fluorescence Resonance Energy Transfer (FRET) cassettes and their corresponding dideoxynucleotide terminators culminated into efficient reagents for DNA sequencing. Additionally, these FRET cassettes/terminators, of the present invention, derived from different classes of heterocyclic systems have high potential to be used for general labelling of biological molecules to generate highly sensitized signals. Their preparation, energy transfer efficiency, and use as labels, specifically, in DNA sequencing reactions is disclosed.</p> |
申请公布号 |
WO2004059011(A1) |
申请公布日期 |
2004.07.15 |
申请号 |
WO2003US40573 |
申请日期 |
2003.12.17 |
申请人 |
AMERSHAM BIOSCIENCES CORP |
发明人 |
NAMPALLI, SATYAM;ZHANG, WEIHONG;RAO, SUDHAKAR;KUMAR, SHIV |
分类号 |
C09B11/08;C09B11/24;C09B23/08;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/00 |
主分类号 |
C09B11/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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