ADIPONECTIN PROMOTER AND USE THEREOF

摘要

DNA having a promoter region containing human adiponectin regulator sequence; a transformant transformed by this DNA; a method of screening a compound promoting the human adiponectin promoter activity with the use of this transformant; a screening kit therefor; a method of screening a preventive/a remedy for various syndromes such as syndrome X, metabolic syndrome, multiple risk factor syndrome, insulin resistance syndrome, deadly quartet and internal fat syndrome, metabolic failures such as diabetes, obesity, hypercholesterolemia and hyperlipoproteinemia, hyperlipemia, arteriosclerosis, hypertension, circulatory diseases, hyperphagia, etc.; and medicinal compositions obtained using the same.