| 发明名称 |
Abin-mediated hepatitis protection |
| 摘要 |
The present invention relates to the use of the A20-binding inhibitor of NF-kappaB activation (ABIN), or a functional fragment or variant thereof to protect aGalNst TNF-induced liver failure, such as viral hepatitis and alcoholic liver disease. More particularly, it relates to the prevention of the toxic effects of said diseases, including lethality, by overexpressing ABIN.
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| 申请公布号 |
US2004136978(A1) |
申请公布日期 |
2004.07.15 |
| 申请号 |
US20030741923 |
申请日期 |
2003.12.19 |
| 申请人 |
BEYAERT RUDI;WIELOCKX BEN;VAN HUFFEL SOFIE;DELAEI FILIP;LIBERT CLAUDE |
发明人 |
BEYAERT RUDI;WIELOCKX BEN;VAN HUFFEL SOFIE;DELAEI FILIP;LIBERT CLAUDE |
| 分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K38/16;A61K38/17;A61K48/00;A61P1/16;A61P31/14;C07K14/47;(IPC1-7):A61K48/00;A61K38/48 |
主分类号 |
C12N15/09 |
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