| 摘要 |
<p>The invention is directed to compositions capable of augmenting the immunogenicity of a vaccine. The composition, or adjuvant, is administered to a mammal in need thereof in sequential or concurrent combination with a vaccine antigen. In one preferred aspect, the adjuvant is provided in the form of a recombinant poxvirus vector, such as a vaccinia virus vector, which comprises a nucleic acid sequence encoding IL-15.</p> |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, ASREPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;PERERA, LIYANGE, P.;WALDMANN, THOMAS, A.;OH, SANG-KON;BERZOFSKY, JAY, A. |
发明人 |
PERERA, LIYANGE, P.;WALDMANN, THOMAS, A.;OH, SANG-KON;BERZOFSKY, JAY, A. |
