NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USETHEREOF AS FACTOR XA INHIBITORS

摘要

The invention relates to novel substituted nitrogen-containing heterobicycle s of general formula (I), wherein B, X1 to X3, and R1 to R5 are defined as indicated in claim 1, the tautomers, enantiomers, diastereomers, mixtures, a nd salts thereof, especially the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties. The compounds of said general formula (I) and the tautomers, enantiomers, diastereomers, mixtures, and salts thereof, especially the physiologically acceptable salts thereof with inorganic or organic acids or bases, and the stereoisomers thereof have valuable pharmaceutical properties, especially an antithrombotic effect and a factor Xa-inhibiting effect.